Djokovic, who won his first Olympic gold medal at the Paris Games in August, won last year’s ATP Finals title by defeating two-time major winner Jannik Sinner in the final.
“I was really looking forward to being there, but due to ongoing injury I won’t be playing next week,” Djokovic posted on his Instagram Story.
“Apologies to those who were planning to see me. Wishing all the players a great tournament. See you soon!”
The top eight players in the world are set to do battle at the ATP Finals from November 10-17 in Turin, Italy.
Sinner, Zverev, four-times grand slam winner Carlos Alcaraz, former US Open champion Daniil Medvedev and American Taylor Fritz have already booked their spots.
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Djokovic’s withdrawal means Casper Ruud (3,855 points), de Minaur (3,745 points) and Andrey Rublev (3720) will make up the rest of the field.
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